LONDON – As the number of people infected with monkeypox doubles every two weeks a group of scientists advising the World Health Organization (WHO) are warning that the window of opportunity to contain the spread is closing rapidly.
Reuters reports that WHO Europe has forecast just over 27,000 monkeypox cases in 88 countries by Aug. 2, up from 17,800 cases in nearly 70 countries at the latest count.
Making predictions beyond that are complex, scientists around the world told Reuters, but there is likely to be sustained transmission for several months and possibly longer, they said.
“We have to get in front of this,” said Anne Rimoin, an epidemiology professor at the University of California, Los Angeles.
“It’s clear the window of opportunity for doing so is closing,” added Rimoin, a member of the WHO expert committee on monkeypox that met last week to determine whether the outbreak constituted a global health emergency.
The WHO’s Director-General Dr. Tedros Adhanom Ghebreyesus declared the escalating global monkeypox outbreak a Public Health Emergency of International Concern (PHEIC) this past Saturday.
Currently, the vast majority of reported cases are in the WHO European Region. “WHO/Europe remains committed to partnering with countries and communities to address the outbreak with the required urgency,” Dr. Tedros said during a media briefing.
While a majority of the science advisors members voted against declaring a PHEIC, Ghebreyesus declared an emergency anyway. Healthcare officials in Europe and the United States are urging that actions stemming from the declaration need to be stepped up including including increased vaccination, testing, isolation for those infected and contact tracing.
“Transmission is clearly unchecked,” Antoine Flahault, director of the Institute of Global Health at the University of Geneva, who chairs the WHO Europe advisory group told the news agency.
Jimmy Whitworth, a professor at the London School of Hygiene and Tropical Medicine, said he expected that cases would not plateau for at least the next four-to-six months, or until the those at highest risk of infection have been either vaccinated or infected. Sexual health organizations recently estimated that could be around 125,000 people in the UK Reuters reported.
Monkeypox has been a globally neglected public health problem in parts of Africa for decades, but cases began to be reported outside countries where it is endemic in May.
Beyond Africa, monkeypox is spreading chiefly in men who have sex with men, putting health clinics under strain as the caseload increases.
“I remember clearly … saying that ‘I think I’m going to die,’ because I can’t eat, I can’t drink. I can’t even swallow my own spit,” said Harun Tulunay, 35, a sexual health advocate who was hospitalized with monkeypox in London earlier this month but has since recovered.
In the United States, the Centers for Disease Control and Prevention on Wednesday noted that there is a total confirmed monkeypox/orthopoxvirus case count of 3,591, the largest concentrations of cases with the states of New York reporting 900, California 356, Illinois 350, Florida 309, Georgia 289 and Texas 223.
Speaking with reporters Tuesday during in a press briefing, White House COVID-19 response coordinator Dr. Ashish Jha addressed the ongoing monkeypox outbreak and the administration’s response.
“The international community must work together to protect individuals that have been impacted by monkeypox and those most at risk of contracting the virus. WHO’s declaration will allow the United States and other partners to better collaborate, to share data, and to get critical information out to high-risk communities,” Jha said.
Jha then pointed out the fact that Biden Administration is keenly aware of the impact that monkeypox is having on the LGBTQ+ community.
“Finally, we’ve been working on the ground with community health partners, members of the LGBT community, and others to ensure that we are getting out good information, that we are addressing concerns that they have, we are listening to their concerns,” he said.
Jha told reporters that the federal government is taking the outbreak of the monkeypox virus seriously and is working on expanding access to testing, vaccines, and treatments, and “making sure that Americans understand what risks and challenges this virus faces and what the administration is doing to respond to it.”
On Wednesday the White House released a statement by HHS Secretary Becerra on FDA Approval of Additional Bavarian Nordic Monkeypox Vaccine. The FDA, CDC, and other agencies have come under fire for being caught unprepared in having vaccines stockpiled to counter the outbreak.
Today, [Wednesday] the Food and Drug Administration (FDA) announced it has approved a supplement to the biologics license for the JYNNEOS Vaccine, which is manufactured by Bavarian Nordic and approved to prevent smallpox and monkeypox Becerra said in the release.
“This action by the FDA is a critical step forward in our plans to strengthen and accelerate our monkeypox response, which includes distributing a safe and effective vaccine to those at highest risk of exposure to monkeypox. The expedited inspection and approval by FDA of Bavarian Nordic’s fill-and-finish capabilities means that an additional 786,000 doses of vaccine are now available for use in the U.S. HHS is working to make these doses available to states and jurisdictions as soon as possible to fulfill their needs and will announce allocations tomorrow.
“Aggressively responding to the monkeypox outbreak is a critical priority for HHS. Within days of the first U.S. case, we activated a multi-pronged response, significantly increasing vaccine supply and distribution, expanding access to tests, making treatments available for free, and educating the public on steps to reduce risk of infection. We will continue to accelerate and strengthen our response in the coming days, and will work with partners on the ground, in the community, and internationally to combat this virus and protect those at risk. I applaud the entire FDA team for their tireless work in making this additional vaccine available as quickly as possible while ensuring it meets the highest standards of quality and safety,” the HHS Secretary added.
During his regular weekly briefing on Wednesday, WHO’s Director-General said; “More than 18 thousand cases of monkeypox have now been reported to WHO from 78 countries, with more than 70% of cases reported from the European Region, and 25% from the Region of the Americas. So far, five deaths have been reported, and about 10% of cases are admitted to hospital to manage the pain caused by the disease.”
Tedros then said:
“This is an outbreak that can be stopped, if countries, communities and individuals inform themselves, take the risks seriously, and take the steps needed to stop transmission and protect vulnerable groups.
The best way to do that is to reduce the risk of exposure. That means making safe choices for yourself and others.
For men who have sex with men, this includes, for the moment, reducing your number of sexual partners, reconsidering sex with new partners, and exchanging contact details with any new partners to enable follow-up if needed.
The focus for all countries must be engaging and empowering communities of men who have sex with men to reduce the risk of infection and onward transmission, to provide care for those infected, and to safeguard human rights and dignity.”
“Stigma and discrimination can be as dangerous as any virus, and can fuel the outbreak,” he added.
Center for Black Equity awarded grant to combat monkeypox
The grant funds the continuing fight against monkeypox misinformation and lack of access to vaccines & resources within minority communities
WASHINGTON – The Center for Black Equity (CBE) has received a $50,000 grant supporting the center’s mission to raise awareness about monkeypox in Black and Latinx LGBTQ communities. The grant will also fund the center’s continuing fight against monkeypox misinformation and lack of access to vaccines and resources within these communities.
The grant, which is a part of a partnership with Gilead Pharmaceuticals, requires the CBE to demonstrate that it has the history and capacity to create and implement a community-wide initiative focusing on monkeypox education and boosting vaccination rates in the Black and Latinx LGBTQ communities.
The CBE is a coalition of international LGBTQ community members, Pride organizations, and community-based organizations that have conducted philanthropic and advocacy work in the LGBTQ community for more than 20 years.
Grant funds will be used in efforts to connect Black and Latinx LGBTQ persons with local community-based organizations that will provide accurate and up-to-date information on monkeypox, direct people to vaccination sites, and improve these communities’ access to monkeypox education and vaccines.
The official kickoff of the CBE’s monkeypox initiative started with a nationwide community leader talk.
“We brought together all of the Black Pride leaders from around the country to talk about monkeypox in their communities, what kind of resources they have, what has been the health department response and what do they need to do their work better,” CBE deputy director Kenya Hutton said.
The CBE will continue to host regular talks with community leaders to support the center’s goal of connecting the needs and voices of the Black and Latinx LGBTQ communities on a nationwide level.
“It’s going to get an idea of what it sounds like or what experiences are from community leaders on the ground level,” Hutton said.
Since monkeypox was officially labeled a public health emergency in the U.S., the LGBTQ community has been vocal about the misinformation surrounding the disease as well as limited resources for LGBTQ communities of color. Many have compared the public health response to monkeypox to the early response to the HIV/AIDS epidemic in the 1980s.
“In the beginning, the information seemed to focus on white gay men,” Hutton said. “And even though they keep saying the number of monkeypox cases are decreasing, the numbers are increasing in the Black and Latinx communities.”
The CBE has an interactive map on its website where you can input your zip code and find permanent and pop-up vaccination sites near you. You can also sign up for the CBE’s biweekly newsletter with up-to-date monkeypox information online.
GLAAD examines impact of HIV, COVID, & MPV in new report
A new GLAAD report is out. Invisible People: A Retrospective Report On The Impacts of COVID & HIV In The United States
By Darian Aaron | NEW YORK – On October 6, in a TIME Magazine exclusive, GLAAD released “Invisible People,” a first-of-its-kind report detailing the disruption caused by COVID-19 in the lives of people living with HIV. The 23-page report combines a comprehensive analysis of peer-reviewed scientific literature, qualitative interviews of people living with HIV, affected communities, and community-based organizations (CBOs) serving these populations.
With research conducted by global market research company Ipsos and completed before the U.S. emergence of the monkeypox virus (MPV), GLAAD has included an MPV addendum to the report that elevates the disproportionate impact of MPV, HIV, and COVID-19 among Black Americans. Through data and first-person narratives, the report highlights the source of medical mistrust in Black communities, examines the lack of access to consistent healthcare during the pandemic, and most recently, inadequate access to the JYNNEOS MPV vaccine, despite the disproportionate occurrence of MPV among Black gay and bisexual men.
GLAAD President Sarah Kate Ellis draws a parallel between the devastating outcomes for LGBTQ people of color across the three major health crises.
“LGBTQ people and queer people of color are disproportionately affected in the pandemic, yet data collection didn’t begin for months to help guide responses and resources, and our voices were vastly underreported across the media,” Ellis says. “These are painful parallels to the early days of HIV/AIDS when GLAAD was formed to fight inaccuracy and invisibility.”
As of October 12, the Centers for Disease Control and Prevention (CDC) has confirmed 27,022 MPV cases across the United States. A steady decline in new cases—a national seven-day moving average of 63 cases as of October 12—is attributed to vaccinations and behavioral changes among gay and bisexual men. However, data from the CDC confirms that while Black and Latino gay and bisexual men represent the overwhelming majority of MPV cases, white and Latino men have received their first dose of the vaccine at a much higher rate.
The inequity in vaccine distribution and the reality that unvaccinated people are 14 times more likely to acquire MPV has exacerbated racial healthcare disparities in Black communities that existed long before the current outbreak.
Is history repeating itself?
In a separate interview, pioneering HIV activist Phill Wilson, founder of The Black AIDS Institute, says the “parallels are scary” in the context of the U.S. response to the early HIV/AIDS crisis and the slow response to the threat of MPV among Black gay and bisexual men in 2022.
“During the early days of the HIV/AIDS pandemic, I used to quote my grandmother—probably your grandmother, too: “When white people get a cold, Black people get pneumonia,” Wilson says.
“The parallels are scary—first, the denial, then the blaming, then the slow response and missed opportunities. And finally, the disproportionate impact on Black, other POC (people of color), and poor communities,” he adds.
“All the earliest information about how the COVID-19 pathogen was transmitted said that Black, brown, and poor people would be disproportionately impacted. And yet, those in power did not develop strategies targeting those communities. The opposite happened.”
A California resident, Wilson provides a first-person account of his vaccination experience in Van Nuys, a suburb of Los Angeles situated in the San Fernando Valley.
“I showed up at the pop-up vaccination station at about 10:15 in the morning. They didn’t open until 11:00 am. There were already 100 people in line,” Wilson says. “They had 400 vaccines available that day. By the time I left at 3:00 pm, they had closed the line for the day. I counted less than five Black men, four or five Latino men, and maybe one Asian man getting vaccinated. Four hundred, presumably LGBTQ+ people, were vaccinated that day, and less than 3% were BIPOC (Black Indigenous People of Color).”
To combat the inequity in the MPV vaccine rollout, the CDC has created a Vaccine Equity Pilot Program to reach populations most affected by MPV but less likely to be vaccinated.
In the report, GLAAD also calls out the inherent homophobia that precipitated the naming of HIV as a “gay disease” in the early days of the epidemic. This stigmatizing language has also been echoed during the recent MPV outbreak because most cases are among gay and bisexual men.
Ryan Lee, an Atlanta-based writer, was diagnosed with MPV in July and has since recovered. He says he understands why gay men are reluctant to bare the social responsibility of MPV.
“The burden and shame that gay men have borne regarding our sexual health have created generational trauma and anxieties. And five months of monkeypox have already stoked the bigotry and judgment in those who love telling gay folks how sick and dirty we are,” Lee says.
“So I understand the reluctance of queer folks to be closely associated with a new illness, but we must recognize monkeypox is currently a disease that disproportionately impacts gay men.”
According to reports published in August, the fear and anxiety experienced by many gay and bisexual men and the refusal of some phlebotomists to administer the MPV vaccine are reminiscent of a dark era in our nation’s history that many hoped never to repeat.
“There is something spooky about sitting in a folding chair in 2022, surrounded by other gay men in folding chairs, waiting to be vaccinated by healthcare workers who wear personal protective equipment and immediately wipe down each vacated chair with disinfectant,” says Amanda Cary, manager for the gay men’s sexual health clinic at Whitman-Walker in D.C, in a story published in The Washington Post.
“Invisible People” lays bare the outcome of slow to no inaction when three health crises converge and target an already marginalized group of people. Through this report, GLAAD continues to elevate the stories and voices of LGBTQ people living with HIV at greater risk for COVID and MPV acquisitions.
“We have to learn from the lessons of each epidemic to be better prepared for the next,” says Andres Cantero Jr., a study participant. “People living with HIV, like all chronic conditions, should know that we can count on care that keeps us alive and helps prevent the spread of HIV.”
“We just lost two years,” says Ellis. “We need folks to look up, wake up, and realize that we as a community and a country can walk and chew gum at the same time. We can deal with a major pandemic while not forgetting about our most marginalized folks.”
Read the complete GLAAD report Invisible People: A Retrospective Report On The Impacts of COVID & HIV In The United States.
Darian Aaron is the MPV project coordinator for GLAAD. He is also communications director of CNP (Counter Narrative Project), and editor-at-large of CNP’s digital publication The Reckoning.
His work can also be read across multiple platforms as a contributor for Q Digital. Follow him on Twitter @darianoutloud.
LA County Public Health expands Monkeypox vaccination eligibility
Eligible residents can go to a Public vaccinating site or visit Myturn.ca.gov to find other vaccinating sites near you
LOS ANGELES – The Los Angeles County Department of Public Health has expanded eligibility to the monkeypox vaccine to closely align with the Centers for Disease Control and Prevention’s recent expansion, which includes persons in select occupational groups whose jobs may expose them to orthopoxviruses (such as monkeypox).
Monkeypox vaccine will be available to residents who self-attest to being in the following groups:
- Gay, bisexual or other men who have sex with men or transgender people who have sex with men or other transgender people
- Persons of any gender or sexual orientation who engage in commercial and/or transactional sex
- Persons living with HIV, especially persons with uncontrolled or advanced HIV disease
- Persons who had skin-to-skin or intimate contact with someone with suspected or confirmed monkeypox, including those who have not yet been confirmed by Public Health
- (NEW) Sexual partners of people in any of the above groups
- (NEW) People who anticipate being in any of the above groups
Monkeypox vaccine is also available for persons in select occupational groups whose may be exposed to orthopoxviruses including:
- Research laboratory personnel working with orthopoxviruses
- Clinical laboratory personnel performing diagnostic testing for orthopoxviruses
- Designated public health response team members
- Health care personnel who administer ACAM2000 (Smallpox [Vaccinia] Vaccine)
- Designated health care workers who care for persons with suspected or confirmed orthopoxvirus infections, including clinicians and environmental services personnel
Note that the risk of monkeypox transmission remains very low for health care workers if appropriate personal protective equipment is worn and other infection control practices are followed.
Residents do not need to show ID in order to get a vaccine at sites run by Public Health. However, because residents may need to show vaccination record and ID if you travel or visit certain venues, it is recommended that when getting a vaccine that residents provide the name that is on their ID.
Residents who met prior eligibility criteria can still get vaccinated (see below for prior criteria).
Gay or bisexual men or transgender people who:
- Had multiple or anonymous sex partners in the past 14 days
- Had skin-to-skin or intimate contact with persons at venues or events in the past 14 days
- Had a history of early syphilis or gonorrhea in the past 12 months
- Are on HIV pre-exposure prophylaxis (PrEP)
- Had anonymous sex or sex with multiple partners in the past 21 days in a commercial sex venue or other venue.
Residents who have monkeypox symptoms or are currently under isolation for monkeypox, should not come to the vaccination clinics or walk-up sites. If residents think they have monkeypox, they should speak with a provider and get tested. If residents do not have a provider, residents can call the Public Health Call Center for more information on monkeypox, including general information, testing, treatment, and vaccines at (833) 540-0473 (open 7 days a week 8am – 8:30pm).
For more information, please visit: http://publichealth.lacounty.gov/monkeypox/.
Los Angeles County Supervisors approve sick leave for monkeypox
Both coronavirus and the monkeypox outbreak has disproportionately affected essential workers, who are predominantly Black and Latino
LOS ANGELES – The Los Angeles County Board of Supervisors unanimously passed a motion Tuesday, sponsored by Supervisors Hilda Solis and Sheila Kuehl, which directs County attorneys to report back to the board in three weeks on how the County could implement a paid sick leave policy for people who contract monkeypox, or other new and emerging infectious diseases.
The Board also is urging California Governor Gavin Newsom to extend the state’s coronavirus supplemental paid sick leave by signing the AB-152 COVID-19 relief leave bill.
Supervisor Solis prior to the vote pointed out that both coronavirus pandemic and the monkeypox outbreak has disproportionately affected essential workers, who are predominantly Black and Latino.
Solis further noted that without a form of paid sick leave, are in most cases, unable to take the recommended five to 10 days to isolate for COVID-19 — much less the two to four weeks needed to isolate for the duration of a monkeypox diagnosis as recommended by the Centers for Disease Control and Prevention as well as the County Dept. of Public Health .
During a monkeypox townhall hosted by the Blade in East Los Angeles last week, which was also attended by Supervisor Solis, Sherrill Brown, M.D, AltaMed’s Medical Director of Infection Prevention, in her presentation noted the need for economic relief.
In her practice treating primarily Latino monkeypox cases at AltaMed clinics in Los Angeles and Orange Counties, she told the townhall attendees she was hearing some of her patients were having difficulty with the required isolation protocols because of their economic needs.
Unvaccinated 14 times more likely to contract monkeypox
Racial disparities persist in new cases of monkeypox as Black & Latino people are overrepresented in the numbers
WASHINGTON – U.S. health officials are celebrating preliminary data on the vaccine used in the monkeypox outbreak, which has led them to conclude eligible persons who didn’t get a shot were 14 times more likely to become infected than those who are vaccinated.
The new data, as described by health officials on the White House monkeypox task force during a call with reporters on Wednesday, comes as the overall number of new cases of monkeypox is in sharp decline, although considerable racial disparities persist in the remaining cases as Black and Latino people are overrepresented in the numbers.
Rochelle Walensky, director of the Centers for Disease Control & Prevention, said during the conference call the preliminary data — collected from 32 states between July 2022 and September 2022 — provides an early shapshot of the effectiveness of the vaccine and cause for optimism on the path forward.
“These new data provide us with a level of cautious optimism that the vaccine is working as intended,” Walkensky said. “These early findings and similar results from studies and other countries suggest even one dose of the monkeypox vaccine offers at least some initial protection against infection.”
Walensky during the conference call admitted the data is incomplete in numerous ways. For example, the data is based on information on individuals who have obtained only the first shot as opposed to both shots in the two-shot vaccination process. (The data showing positive results from individuals who have only one shot contradicts previous warnings from the same U.S. health officials that one shot of the monkeypox vaccine was insufficient.)
The data also makes no distinction between individuals who have obtained a shot through subcutaneous injection, a more traditional approach to vaccine administration, as opposed to intradermal injection, which is a newer approach adopted in the U.S. guidance amid the early vaccine shortage. Skeptics of the new approach have said data is limited to support the idea the intradermal injection is effective, particularly among immunocompromised people with HIV who have been at higher risk of contracting monkeypox.
Not enumerated as part of the data were underlying numbers leading health officials to conclude the unvaccinated were 14 times more likely to contract monkeypox as opposed to those with a shot, as well as any limiting principle on the definition of eligible persons. Also unclear from the data is whether individual practices in sexual behavior had any role in the results.
Despite the positive data on the monkeypox vaccine based on one shot, U.S. health officials warned during the conference call the two-shot approach to vaccine administration is consistent with their guidance and more effective.
Demetre Daskalakis, the Biden administration’s face of LGBTQ outreach for monkeypox and deputy coordinator for the White House monkeypox task force, made the case that for individuals at risk obtaining a second dose is “really important.”
“So we see some response after the first [shot] in the laboratory, but the really high responses that we want to really get — that you know, level 10 forcefield as opposed to the level five forcefield — doesn’t happen until the second dose,” Daskalakis said. “So the important message is this just tells us to keep on trucking forward because we need that second dose at arms that people haven’t gotten the first should start their series of two vaccines.”
Also during the call, health officials said they would be expanding opportunities for vaccines as pre exposure prophylaxis, as opposed to practices in certain regions granting vaccines in their limited supply to individuals who meet certain criteria or have had risk of exposure.
The Centers of Disease Control & Prevention, officials said, is also updating its guidance to allow injection of the vaccines in places other than a patient’s arm.
Daskalakis said fear of stigma about getting a noticeable shot in the forearm after obtaining a monkeypox vaccine was a key part of the decision to issue the new guidance on implementation.
“Many jurisdictions and advocates have told us that some people declined vaccine to monkeypox because of the stigma associated with the visible but temporary mark often left on their forearm,” Daskalakis said. “New guidance from CDC allows people who don’t want to risk a visible mark on their forearm to offer a vaccine on their skin by their shoulder or their upper back. Those are areas more frequently covered by clothes.”
Supervisor Hahn to host Downey & Long Beach vax pop-ups
“This vaccine is critical to keeping people safe from the MPOX virus and I want to make it as easy as possible for people to get vaccinated”
DOWNEY, Ca – Los Angeles County Supervisor Janice Hahn will host a series of Mpox vaccine pop-up clinics outside of bars in Downey and Long Beach this coming weekend. These follow a successful Mpox vaccine pop-up that the Supervisor held outside of Hamburger Mary’s in Long Beach earlier this month, where 67 people received a dose.
“This vaccine is critical to keeping people safe from the MPOX virus and I want to make it as easy as possible for people to get vaccinated,” said Supervisor Hahn. “I am partnering with the LA County Department of Public Health, Long Beach Public Health, and the City of Downey to bring these pop-up vaccine clinics to places where people spend their free time and that are considered safe spaces by the LGBTQ+ community.”
Muevelo Fridays is an LGBTQ+ Latino dance party held once a week at The Epic Lounge in Downtown Downey. Falcon and Falcon North are well-established bars serving Long Beach’s LGBTQ+ community. The Falcon is located on East Broadway, home to several other gay bars that attract people from across the region.
“We appreciate that the Supervisor listens to community concerns, especially when it comes to public health, and we’re grateful that she’s using her resources at the county level to bring the mobile testing unit to Downey,” said Downey Councilman Mario Trujillo, who worked with Supervisor Hahn’s office to bring the pop-up to Downey on Friday. “We invite Downey residents and residents from surrounding communities to take advantage of the unit that’s being brought locally for their benefit.”
The vaccine pop-ups are carried out using a cargo van mobile unit. Supervisor Hahn purchased one of these mobile vans to bring COVID-19 vaccines to communities across her district.
On-site vaccination staff are employees of the Los Angeles County and Long Beach public health agencies.
What: Supervisor Janice Hahn Mpox vaccine pop-ups
|Friday, September 23, 8pm to 10:30pm|
The Epic Lounge
8239 2nd St., Downey, CA 90241
|Saturday, September 24, 8pm to 12am|
1435 East Broadway, Long Beach, California 90802
|Sunday, September 25, 5pm to 9pm|
2020 East Artesia Boulevard, Long Beach, California 90805
Racial disparities persist in monkeypox outbreak
With the racial disparity ongoing, health observers say additional efforts are needed to reach out to marginalized communities
WASHINGTON – Racial disparities persist in response to the monkeypox outbreak as the numbers of Black and Latino men contracting the disease are now disproportionately high, but that inequity is getting new attention as overall cases drop.
Although overall new cases in the monkeypox outbreak are steadily on the decline after numbers peaked in the summer, a growing share of the continuing numbers belong to men who have sex with men who are racial minorities.
The latest numbers show the racial disparity dramatically. In the week of Sept. 4, Black people consisted of 41 percent of the cases and Latinos consisted of 27 percent, while 26 percent were white and three percent were Asian, according to data from the Centers for Disease Control.
Black people among the new cases of monkeypox were much smaller when numbers were first reported earlier in the summer. For example, the percentage was 18 on June 22 and as low as 8 percent June 8. The percentage of Latinos, as with white people, has been on the decline, although they’re still overrepresented in new cases in the context of their demographics in the U.S. population at large.
The disproportionate impact of new monkeypox cases on racial minorities hasn’t gone unnoticed. As a result, health officials are attempting to shift the focus of the monkeypox outbreak away from gay and bisexual men and other men who have sex with men more broadly and more toward men of color who are sexual minorities.
Sean Cahill, director of health policy research at the Boston-based Fenway Institute, said in an interview with the Washington Blade the racial disparities in the monkeypox outbreak are largely the result of Black and Latino men being “less likely to get vaccinated than their proportion of the population.”
“So they’re more vulnerable to monkeypox, and they’re less likely to get the vaccine,” Cahill said. “So that’s a real problem, and it’s really critical that you know, federal, state and local partners come together and really center equity in the response and try to reduce the burden on Black and Latino gay men, but also increase access to the vaccine to ensure that people can protect themselves.”
The Fenway Institute last week issued a blueprint calling for a more effective federal response to monkeypox, accusing the U.S. government of failing to effectively mobilize existing public health infrastructure to aid communities affected by the virus. The document outlines a range of possible actions, but also concludes marginalized communities are having difficulty accessing vaccines and treatments, which are concentrated at well-resourced institutions less accessible to communities of color.
Cahill, asked to characterize whether the numbers demonstrating racial disparity have changed over time or have remained stagnant, said any trends are difficult to determine because the data on racial demographics has been available only recently and “it’s very imperfect data.”
“I don’t know if it’s getting worse or better, the disproportionate racial ethnic impact,” Cahill said. “But it’s definitely there, and it doesn’t seem to be going away.”
The Biden administration, while touting the 20 percent decline in overall cases in the monkeypox outbreak, has also started to recognize the continued disproportionate impact of monkeypox on Black and Latino men who have sex with men.
Rochelle Walensky, director for the Centers for Disease Control & Prevention, said during a conference call with reporters the U.S. government approaches the decline with “cautious optimism.”
“Over the past several weeks, we have also seen the racial and ethnic makeup of this outbreak evolve,” Walensky said. “While monkeypox cases were first seen predominantly in non-Hispanic white men, in the last week, among the cases for which we have race and ethnicity data, non-Hispanic Black men represented 38 percent of cases, Latino or Hispanic men represented 25 percent of cases, and non-Hispanic white men represented 26 percent of cases.”
Among the efforts the Biden administration has undertaken is a pilot program for vaccines reserved for large events and equity. Monkeypox vaccines have been administered to more than 10,000 people, including at Southern Decadence in New Orleans, Atlanta Black Gay Pride, Charlotte Pride, Boise Pride Festival, and Oakland Pride and Pridefest.
Dr. Demetre Daskalakis, the face of LGBTQ outreach for the Biden administration in monkeypox efforts and deputy director the White House monkeypox task force, was among those promoting the pilot program in equity efforts during a conference call with reporters.
“Health departments will use their local experience and connection to the community to identify hyperlocal strategies to improve vaccine access to communities of color, specifically those that are overrepresented in this outbreak,” Daskalakis said.
David Johns, executive director of the National Black Justice Coalition, said in the racial disparities in the monkeypox outbreak are consistent with other trends in public health.
“There have been so many opportunities to learn ways to address health inequities before they grow,” Johns said. “That Black people continue to be disproportionately impacted by this newest health epidemic is additional evidence of how white supremacy works and the importance of democratized responses to crises.”
Biden health officials, asked by the Washington Blade during the virtual meeting why the administration’s stated goal of equity in managing the monkeypox outbreak isn’t producing racial equity among new cases, restated their efforts and talked about the difficulty in achieving that goal.
Walensky, who has also had a lead role in the Biden administration combating the coronavirus pandemic, said racial disparities in the monkeypox outbreak “is not uncommon for many infectious diseases, quite unfortunately,” and defended the U.S. government’s approach to monkeypox.
“And it is exactly for these reasons why we started on these pilot projects before we even saw the shifts in data, as that is often the case in infectious diseases that we have more vulnerable population — racial and ethnic minorities — who are most impacted later on,” Walensky added. “And so, we anticipated this. We have embarked on these activities to address this in exactly this moment.”
Daskalakis, following up in defense of the Biden administration’s efforts on equity, said he’s “spoken to providers on the ground and also promoters at these events who have noted that this effort is really unprecedented in terms of reaching deeply into these communities.”
“I think all of our commitment in the administration is to really focus efforts on equity to resolve the issues that we’re seeing. It is a hard effort and it’s a challenge,” Daskalakis added. “And I think that the way to address equity is intentionally, and this is an example of intentional work to address equity.”
With the racial disparity in the monkeypox outbreak ongoing, health observers say additional efforts are needed to reach out to marginalized communities to ensure they have access to public messaging and vaccinations.
Cahill said although people of color in urban areas go to LGBTQ centers to receive health care, many of them are also getting care through other facilities that aren’t LGBTQ-specific, such as emergency rooms and urgent care clinics .
“I think providing some training and technical assistance to those healthcare organizations in how to provide affirming care to bisexual men could be an important approach and could make it so that people might be more likely to disclose same-sex behavior in those contexts,” Cahill said.
LA County Public Health confirms first death due to Monkeypox
The patient was severely immunocompromised & hospitalized. To protect confidentiality & privacy additional information won’t be made public
LOS ANGELES – In a press statement issued Monday afternoon, the Los Angeles Department of Public Health, along with the Centers for Disease Control and Prevention (CDC), has confirmed the first death due to monkeypox in a Los Angeles County resident.
According to the statement the resident was severely immunocompromised and had been hospitalized. To protect confidentiality and privacy, additional information on this case will not be made public the statement added.
LA County Public Health Chief Medical Director Rita Singhal had told reporters last week during a briefing that this second possible death from monkeypox in the U.S. was under investigation.
In the first case, NBC News reported that in late August, the Texas Department of State Health Services reported that a person diagnosed with monkeypox in the Houston area had died. The patient was described in a statement as “severely immunocompromised.”
The role of monkeypox in the patient’s death was under investigation, Texas officials said at the time.
The Centers for Disease Control and Prevention said Friday that a case analysis found that 61% of people in the U.S. who have developed monkeypox also had HIV or another sexually transmitted infection or disease.
Monkeypox cases data in LA County as of September 9, 2022 showed 1,836 cases which included the cities of Long Beach and Pasadena which have separate health departments.
Los Angeles County (excl. Long Beach and Pasadena)1,722, Long Beach 92, and Pasadena 22.
NIH says clinical trial evaluating antiviral for monkeypox begins
Phase 3 clinical trial is now enrolling adults and children with monkeypox infection. Adults and children of any age are eligible to enroll
BETHESDA, Md. – A clinical trial evaluating antiviral for monkeypox has started enrolling volunteers for a study of Tecovirimat (TPOXX), an antiviral drug approved by the U.S. Food and Drug Administration for the treatment of smallpox.
In an announcement Friday by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, officials noted that a Phase 3 clinical trial evaluating the antiviral drug is now enrolling adults and children with monkeypox infection in the United States.
The drug prevents the virus from spreading in the body by preventing virus particles from exiting human cells by targeting a protein found on both the variola virus, which causes smallpox, and the monkeypox virus. Clinicians currently can access tecovirimat for U.S. patients with monkeypox through an expanded access or “compassionate use(link is external)” request process.
“Monkeypox can be an extremely painful infection that lasts for weeks,” said NIAID Director and President Joe Biden’s Chief Medical Advisor Dr. Anthony S. Fauci, “We currently lack efficacy data that would help us understand how well this drug may mitigate painful monkeypox symptoms and prevent serious outcomes. This clinical trial was designed to answer those important questions.”
The clinical trial of tecovirimat in the United States is led by Timothy Wilkin, M.D., professor of medicine at Weill Cornell Medicine in New York City. Adults and children of any age with monkeypox are eligible to enroll in the trial. Adults with severe monkeypox virus infection or those at high risk for severe disease including individuals with underlying immune deficiency, a history of or active inflammatory skin conditions, pregnant people and children all will be enrolled in an open-label arm in which all participants receive tecovirimat.
Other adult participants—530 total—will be randomly assigned in a 2:1 ratio to receive tecovirimat or placebo pills. Tecovirimat capsules are taken by mouth for 14 days, and the dose is based on the participant’s weight. This part of the trial is double-blind, meaning neither participants nor investigators will know who is receiving placebo or tecovirimat.
Investigators will gather data to determine if participants receiving tecovirimat heal more quickly (all lesions scabbed over or flaked off) compared with those taking placebo. They also will examine tecovirimat’s impact on pain scores, rates of progression to severe disease, clearance of monkeypox virus from various samples, and its safety, among other data. This study also will provide critical data on the optimal dosing and safety of tecovirimat in children and people who are pregnant.
Participants will be followed for at least 8 weeks and will be asked to fill out a symptom diary, do daily skin checks at home and attend virtual and in-person clinic appointments. They also will undergo physical exams and will be asked to provide blood and other bodily fluid samples, including swabbing fluid from their lesions.
Data on the safety and efficacy of tecovirimat will be submitted to the FDA. An independent Data and Safety Monitoring Board (DSMB) will monitor participant safety throughout the duration of the study. The trial timeline will depend on the pace of enrollment.
A global outbreak of human monkeypox virus, first identified in May 2022, prompted public health emergency declarations from both the World Health Organization (WHO) and the U.S. Department of Health and Human Services this past summer. The majority of cases identified thus far have been in men who have sex with men, although other populations, including women and children, can become infected. From Jan. 1, 2022, to Sept. 7, 2022, the WHO has reported 52,996 cases and 18 deaths across 102 countries, territories and areas. The Centers for Disease Control and Prevention has reported 21,504 cases in the U.S.
Prior to the global outbreak, monkeypox cases and outbreaks were mostly confined to countries in central and west Africa, where the virus is endemic. Monkeypox can cause flu-like symptoms and painful skin lesions. In rare cases, monkeypox virus can cause serious complications, including dehydration, bacterial infections, pneumonia, brain inflammation, sepsis, eye infections and death. The virus can be transmitted from person to person through direct contact with skin lesions, body fluids, and respiratory droplets, including through intimate contact, particularly sexual contact, and by indirect contact with items such as contaminated clothing or bedding. Preliminary analyses indicate that sexual transmission may be playing a role in the current outbreak.
Monkeypox vaccine effort shifts toward maintaining demand
Supply issues resolved, focus remains on addressing racial disparities in rates of infection and vaccination
WASHINGTON – As ensuring adequate supply and distribution of the monkeypox virus (MPV) vaccine becomes “less of an issue,” efforts have shifted toward maintaining demand, Dr. Demetre Daskalakis, White House national monkeypox response deputy coordinator, said on Wednesday.
This will mean, “making sure that people know that a effective and safe vaccine is available for those that could benefit,” he said, during a press briefing that also featured National Response Coordinator Dr. Bob Fenton and White House Press Secretary Karine Jean-Pierre.
The officials said they were pleased with the impact of their targeted allocations of vaccine doses to events with large numbers of gay and bisexual men who have sex with men, populations considered high risk for MPV infection.
“Thousands of shots were administered” at Southern Decadence in New Orleans, Black Pride in Atlanta, and Oakland Pride in the Bay Area, Dr. Fenton said. These efforts “were, frankly, wildly successful,” Dr. Daskalakis said.
During a Q&A with reporters that followed the briefing, Dr. Daskalakis addressed questions about the racial disparities that have begun to emerge with respect to infection and vaccination rates.
According to the Kaiser Family Foundation, “Black people have received 22% vaccines, while they account for 36% of cases. In contrast, White people have received 63% of vaccinations but account for 42% of cases.”
Dr. Daskalakis explained the events that were targeted this summer were a major part of addressing the disproportionately higher rates of infection and lower rates of vaccination among people of color.
“It’s not about just the vaccine allocation,” he said. “It’s about that intense community engagement that happens on the ground because, ultimately, public health is a local event.”
From the beginning of the outbreak, those engaged in the federal response were in touch with community organizations, Dr. Daskalakis said: “Giving the tools that people need to be able to sort of reach health goals is what we’ve been doing. And the support of organizations that serve Black and brown people have been pivotal in really turning the tide in what I think you’re going to see, the new vaccine numbers emerging over the next few weeks.”
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